Acupuncture & Parkinson’s

BMC Complement Altern Med. 2014 Sep 15;14:336. doi: 10.1186/1472-6882-14-336.

Acupuncture on GB34 activates the precentral gyrus and prefrontal cortex in Parkinson’s disease.

Author information

  • 1Research Group of Pain and Neuroscience, WHO Collaborating Centre, East-west Medical Research Institute, Kyung Hee University, Seoul, Republic of Korea. lims@khu.ac.kr.

Abstract

BACKGROUND:

Acupuncture is increasingly used as an additional treatment for patients with Parkinson’s disease (PD).

METHODS:

In this functional magnetic resonance imaging study, brain activation in response to acupuncture in a group of 12 patients with PD was compared with a group of 12 healthy participants. Acupuncture was conducted on a specific acupoint, the right GB 34 (Yanglingquan), which is a frequently used acupoint for motor function treatment in the oriental medical field.

RESULTS:

Acupuncture stimulation on this acupoint activates the prefrontal cortex, precentral gyrus, and putamen in patients with PD; areas that are known to be impaired in patients with PD. Compared with healthy participants, patients with PD showed significantly higher brain activity in the prefrontal cortex and precentral gyrus, especially visible in the left hemisphere.

CONCLUSIONS:

The neuroimaging results of our study suggest that in future acupuncture research; the prefrontal cortex as well as the precentral gyrus should be treated for symptoms of Parkinson’s disease and that GB 34 seems to be a suitable acupoint. Moreover, acupuncture evoked different brain activations in patients with Parkinson’s disease than in healthy participants in our study, stressing the importance of conducting acupuncture studies on both healthy participants as well as patients within the same study, in order to detect acupuncture efficacy.

TRIAL REGISTRATION:

KCT0001122 at cris.nih.go.kr (registration date: 20140530).

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Acup on GB34 activates precentral gyrus & prefrontal cortex in Parkinson’s

 

 

Year : 2013  |  Volume : 8  |  Issue : 6  |  Page : 540-549

Electroacupuncture-regulated neurotrophic factor mRNA expression in the substantia nigra of Parkinson’s disease rats


1 Department of Acupuncture and Moxibustion, Third Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou 310005, Zhejiang Province; Teaching and Research Office of Acupuncture, College of Acupuncture & Orthopedics, Hubei University of Chinese Medicine, Wuhan 430065, Hubei Province, China
2 Department of Acupuncture and Moxibustion, Third Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou 310005, Zhejiang Province, China
3 Teaching and Research Office of Acupuncture, College of Acupuncture & Orthopedics, Hubei University of Chinese Medicine, Wuhan 430065, Hubei Province, China

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Electro-acup & Parkinson’s Neural Regen Res86540-9486666_023806

Date of Submission 23-Aug-2012
Date of Acceptance 20-Nov-2012
Date of Web Publication 11-Dec-2013

 

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